Take this medicine only as directed. Do not take more of it and do not take it more often than your doctor ordered. To do so may increase the chance of serious side effects. To help clear up your infection completely, take this medicine in regularly spaced doses as ordered by your doctor.
In some infections, a second treatment with this medicine may be required to clear up the infection completely. Do not miss any doses. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine.
Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Do not double doses. Piperazine excretion is fast. It can be detected in urine already 30 minutes after oral administration. Click here for a list and overview of all safety summaries of antiparasitic active ingredients in this site. If you intend to use a veterinary drug containing this active ingredient you must carefully read and follow the safety instructions in the product label.
Always ask your veterinary doctor, or pharmacist, or contact the manufacturer. Be aware that the safety instructions for the same veterinary medicine may vary from country to country.
The information in this page must not be confused with the Materials and Safety Datasheets MSDS officially issued by manufacturers for active ingredients and many other chemicals. MSDSs target safety during manufacturing, transport, storage and handling of such materials. This safety summary is a complement to the information on product labels and MSDS. They are especially effective against adult ascarid roundworms e. Ascaris suum in pigs; Toxocara canis and Toxocara cati in pets, etc.
Oesophagostomum spp. Worm stages in the tissues e. But piperazine salts are ineffective against many parasitic gastrointestinal roundworms of livestock e. This is why they are only scarcely used on ruminants. They are also ineffective against lungworms e. Piperazine derivatives have no residual effect. This means that a single administration will kill the parasites present in the host at the time of treatment, but it will not protect against re-infestations.
Since it is not effective against larvae in the host tissues outside the gastrointestinal tract, re-treatments may be required to ensure control of certain species. Piperazine and pyrantel seem to be pharmacologic antagonists and should not be administered simultaneously.
There are no or pour-ons or spot-ons with piperazine derivatives. Diethylcarbamazine citrate is a particular piperazine derivative vastly used against filarial roundworms in pets e. Onchocerca spp , Wucheria spp, Brugia spp. Diethylcarbamazine is usually delivered as injectable or in the form of tablets, pills, etc. The pharmacokinetic behavior is similar for all piperazine salts.
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